Weight-Loss Medications
Understanding Ozempic®, Wegovy®, Zepbound®, Mounjaro®, and Other GLP-1 Medications
Prescription weight-loss medications have changed the treatment of obesity and have helped many people lose significant amounts of weight. For many patients, these medications can be an effective part of a comprehensive weight-loss program—but they are not the right choice for everyone.
Dr. Bao Nasri believes obesity is a chronic medical condition that should be treated with an individualized approach. Treatment may include lifestyle changes, weight-loss medications, bariatric surgery, or a combination of these therapies depending on your health goals and medical history.
How Do GLP-1 Weight-Loss Medications Work?
GLP-1 medications work by mimicking natural hormones produced in your digestive system after eating. These medications help:
- Reduce appetite
- Increase feelings of fullness
- Slow stomach emptying
- Reduce food cravings
- Improve blood sugar control
Common Weight-Loss Medications
Ozempic® (Semaglutide)
Originally approved to treat type 2 diabetes; commonly prescribed for blood sugar control and may also lead to weight loss.
Wegovy® (Semaglutide)
Same active medication as Ozempic®, approved specifically for chronic weight management in eligible adults and adolescents.
Zepbound® (Tirzepatide)
Approved for chronic weight management; targets GLP-1 and GIP hormones involved in appetite regulation.
Mounjaro® (Tirzepatide)
Approved for type 2 diabetes and often associated with substantial weight loss while improving blood sugar control.
Who May Benefit From Weight-Loss Medication?
- Have obesity or overweight with obesity-related medical conditions
- Have not achieved adequate weight loss with diet and exercise alone
- Prefer a non-surgical treatment option
- Are preparing for bariatric surgery
- Have regained weight after bariatric surgery without an anatomical problem requiring revision
Benefits of GLP-1 Medications
- ✔Reduced appetite
- ✔Steady weight loss
- ✔Improved blood sugar control
- ✔Lower blood pressure
- ✔Improved cholesterol
- ✔Better mobility
- ✔Improved quality of life
Possible Side Effects
- Nausea
- Vomiting
- Constipation
- Diarrhea
- Abdominal discomfort
- Bloating
- Heartburn
- Pancreatitis
- Gallstones disease
Most side effects improve as the body adjusts. Who should not take GLP-1 medications →
When Are Weight-Loss Medications Not Enough?
- Weight-loss plateaus
- Inadequate weight loss
- Weight regain
- Difficulty tolerating side effects
- Obesity-related conditions that may be better treated with bariatric surgery
Weight-Loss Medication vs. Bariatric Surgery
Weight-loss medications and bariatric surgery are not competing treatments—they are both valuable tools for managing obesity. Some patients do very well with medication alone. Others benefit more from bariatric surgery. For some individuals, medications and surgery may be used together as part of a long-term treatment plan.